Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290538 | 0.81 | HTR2C (0.33) | — | |
| SCHEMBL7298705 | 0.79 | HTR2C (0.32) | — | |
| SCHEMBL7300100 | 0.79 | — | — | |
| SCHEMBL7298521 | 0.79 | KMT2A (0.32) | — | |
| SCHEMBL7298538 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL7290527 | 0.75 | P2RY1 (0.34) | — | |
| SCHEMBL7297060 | 0.73 | TDP1 (0.40) | — | |
| SCHEMBL7293357 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL17193997 | 0.69 | MAOB (0.37) | PKMPKLRMAOB | |
| SCHEMBL23422991 | 0.67 | PKM (0.42) | PKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |