Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047540 | 1.00 | RECQL (0.55) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL3485765 | 0.86 | AKR1C3 (0.55) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL83065 | 0.86 | AKR1C3 (0.55) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL9103420 | 0.86 | ABCG2 (0.54) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL3818255 | 0.86 | AKR1C3 (0.55) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL8351839 | 0.84 | AKR1C3 (0.53) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL28732347 | 0.84 | ABCG2 (0.53) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| SCHEMBL1397476 | 0.84 | ABCG2 (0.53) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10437231 | 0.84 | AKR1C3 (0.53) | RECQLAKR1C3ABCG2ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL4743624 | 0.84 | ABCG2 (0.56) | RECQLAKR1C3ABCG2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308785-B1 | DIHYDROPYRIDINE ETHERS, PROCESSES FOR THEIR PREPARATION AND THEIR UTILISATION | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0308785-A2 | Dihydropyridine ethers, processes for their preparation and their utilisation | BAYER AG (DE) | 1989-03-29 | — | — | EP | disclosed |