Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292773 | 0.84 | L3MBTL1 (0.35) | L3MBTL1TDP1MAPTMEN1CYP1A2 | |
| SCHEMBL7292787 | 0.83 | L3MBTL1 (0.35) | L3MBTL1TDP1MAPTKAT2BPDE4D | |
| SCHEMBL7315149 | 0.83 | L3MBTL1 (0.35) | L3MBTL1TDP1MAPTMEN1KMT2A | |
| SCHEMBL7298804 | 0.83 | NPC1 (0.32) | NPC1 | |
| SCHEMBL7375797 | 0.83 | NPC1 (0.32) | NPC1 | |
| SCHEMBL7292898 | 0.83 | NPC1 (0.34) | NPC1 | |
| SCHEMBL7297727 | 0.82 | TDP1 (0.37) | L3MBTL1TDP1MAPTMEN1CYP1A2 | |
| SCHEMBL7298944 | 0.80 | NPC1 (0.37) | TDP1MEN1KMT2AGSK3BNPC1 | |
| SCHEMBL7293126 | 0.79 | MET (0.35) | L3MBTL1TDP1MAPTMEN1CYP1A2 | |
| SCHEMBL7300272 | 0.79 | NPC1 (0.33) | CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0308792-A2 | Azachromane derivatives | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |