Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290618 | 0.89 | MAPK1 (0.56) | MAPK1MEN1KMT2AVCAM1ALDH1A1 | |
| SCHEMBL7289003 | 0.89 | MEN1 (0.43) | MEN1KMT2AGLAALDH1A1MAPT | |
| SCHEMBL7289010 | 0.89 | MEN1 (0.43) | MEN1KMT2AGLAALDH1A1MAPT | |
| SCHEMBL9583479 | 0.89 | MEN1 (0.43) | MEN1KMT2AGLAALDH1A1MAPT | |
| SCHEMBL9585048 | 0.86 | LMNA (0.46) | MAPK1MEN1KMT2AGLAALDH1A1 | |
| SCHEMBL7644495 | 0.84 | MAPT (0.41) | MAPK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7290407 | 0.82 | ABCC3 (0.48) | MAPK1MEN1KMT2AVCAM1ALDH1A1 | |
| SCHEMBL7297457 | 0.80 | MAPK1 (0.56) | MAPK1MEN1KMT2AVCAM1ALDH1A1 | |
| SCHEMBL9585054 | 0.78 | MAPK1 (0.43) | MAPK1MEN1KMT2AGLAVCAM1 | |
| SCHEMBL9585074 | 0.78 | LMNA (0.48) | MAPK1MEN1KMT2AVCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406958-B1 | Positive inotropic and lusitropic 3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0406958-A2 | Positive inotropic and lusitropic 3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-01-09 | — | — | EP | disclosed |