SCHEMBL7299377

SCHEMBL7299377

NC(=NNCN=O)c1ccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCC2)cc1

nearest known ligand 0.80

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 5/20 0.64
PLG P00747 4/20 0.64
PLAU P00749 1/20 0.64
F2 P00734 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8159130 0.85 PLG (0.66) F10PLGPLAUF2
SCHEMBL7439785 0.85 PLG (0.83) F10PLGPLAU
SCHEMBL8955008 0.78 PLG (0.77) F10PLGPLAUF2
SCHEMBL27489065 0.77 PLG (0.67) F10PLGPLAUF2
Hydrochloric Acid SCHEMBL6793275 0.76 PLG (0.66) F10PLGPLAUF2
SCHEMBL7309221 0.75 F10 (0.47) F10PLGPLAUF2
SCHEMBL872422 0.74 PLG (0.67) F10PLGPLAUF2
SCHEMBL8144360 0.74 PLG (0.67) F10PLGPLAUF2
SCHEMBL9189122 0.74 PLG (0.67) F10PLGPLAUF2
SCHEMBL29514928 0.74 PLG (0.67) F10PLGPLAUF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5097793-A None JP disclosed
EP-0508220-B1 Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them BEHRINGWERKE AG (DE) 1995-07-26 EP disclosed
US-5274098-A Amidinophenylalanine derivatives, process for their preparation, their use and compositions containing them BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1993-12-28 US disclosed
JP-H0597793-A AMIDINOPHENYLALANINE DERIVATIVE BEHRINGWERKE AG 1993-04-20 JP disclosed
EP-0508220-A1 Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them BEHRINGWERKE Aktiengesellschaft (DE) 1992-10-14 EP disclosed