Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 5/20 | 0.66 |
| ▸ | F10 | P00742 | 3/20 | 0.66 |
| ▸ | PLAU | P00749 | 2/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | F12 | P00748 | 1/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.57 |
| ▸ | PROC | P04070 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439785 | 0.86 | PLG (0.83) | PLGF10PLAUF12KLKB1 | |
| SCHEMBL7299377 | 0.85 | F10 (0.64) | PLGF10PLAUF2 | |
| SCHEMBL7440975 | 0.82 | F2 (0.53) | PLGF10PLAUF2 | |
| SCHEMBL27489065 | 0.80 | PLG (0.67) | PLGF10PLAUF2 | |
| Hydrochloric Acid SCHEMBL6793275 | 0.79 | PLG (0.66) | PLGF10PLAUF2 | |
| SCHEMBL8955008 | 0.79 | PLG (0.77) | PLGF10PLAUF2F12 | |
| SCHEMBL29651383 | 0.76 | PLG (0.67) | PLGF10PLAUF2F12 | |
| SCHEMBL8144360 | 0.76 | PLG (0.67) | PLGF10PLAUF2F12 | |
| SCHEMBL9189122 | 0.76 | PLG (0.67) | PLGF10PLAUF2F12 | |
| SCHEMBL29514928 | 0.76 | PLG (0.67) | PLGF10PLAUF2F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658585-B1 | Aminophenylalanine derivatives, process for their production, their use and agents containing them as anti-coagulants | STUEBER WERNER (DE) | 2000-07-19 | — | — | EP | disclosed |
| EP-0513543-B1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| EP-0658585-A2 | Aminophenylalanine derivatives, process for their production, their use and agents containing them as anti-coagulants | BEHRINGWERKE Aktiengesellschaft (DE) | 1995-06-21 | — | — | EP | disclosed |
| US-5274098-A | Amidinophenylalanine derivatives, process for their preparation, their use and compositions containing them | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0513543-A1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |