Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.57 |
| ▸ | EPOR | P19235 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9155255 | 0.99 | ITGB3 (0.56) | ITGB3ITGA2BEPORPPARGPPARA | |
| Hydrochloric Acid SCHEMBL7299252 | 0.99 | ITGB3 (0.56) | ITGB3ITGA2BEPORPPARGPPARA | |
| Hydrochloric Acid SCHEMBL7299604 | 0.99 | ITGB3 (0.56) | ITGB3ITGA2BEPORPPARGPPARA | |
| SCHEMBL7292955 | 0.90 | ITGB3 (0.45) | ITGB3ITGA2BPPARGPPARAFFAR1 | |
| SCHEMBL7291522 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BPPARGPPARAFFAR1 | |
| SCHEMBL7391463 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BPPARGPPARAFFAR1 | |
| SCHEMBL10686536 | 0.83 | CYP1A2 (0.43) | PPARGPPARA | |
| SCHEMBL7386323 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL7300626 | 0.82 | KDM4E (0.60) | ITGB3ITGA2B | |
| SCHEMBL7324330 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BEPORPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | claimed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | claimed |
| EP-0478328-A1 | Novel fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | claimed |
| EP-0528586-B1 | Inhibiting osteoclast-mediated bone resorption using aminoalkyl-substituted phenyl derivatives | MERCK & CO INC (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |
| US-5217994-A | METHOD OF INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION BY ADMINISTRATION OF AMINOALKYL-SUBSTITUTED PHENYL DERIVATIVES | MERCK & CO., INC. (US) | 1993-06-08 | — | — | US | disclosed |
| US-5204350-A | Treating osteoporosis | MERCK & CO., INC. (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0528587-A1 | Inhibiting osteoclast-mediated bone resorption using substituted phenyl derivatives | MERCK & CO. INC. (US) | 1993-02-24 | — | — | EP | disclosed |
| EP-0528586-A1 | Inhibiting osteoclast-mediated bone resorption using aminoalkyl-substituted phenyl derivatives | MERCK & CO. INC. (US) | 1993-02-24 | — | — | EP | disclosed |