Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292687 | 0.91 | ITGB3 (0.62) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL9305777 | 0.85 | ITGB3 (0.46) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL7291522 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7391463 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7292955 | 0.82 | ITGB3 (0.45) | KDM4EALDH1A1NPC1RAB9AITGB3 | |
| SCHEMBL7299382 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL7283094 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9155255 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7299252 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7299604 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0478328-A1 | Novel fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | claimed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |