Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499119 | 0.90 | PNMT (0.39) | PNMTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL28463245 | 0.78 | PNMT (0.51) | PNMTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL28918336 | 0.76 | PNMT (0.43) | PNMTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL4059189 | 0.75 | PNMT (0.54) | PNMTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL31164036 | 0.75 | PNMT (0.46) | PNMTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL28857904 | 0.75 | PNMT (0.46) | PNMTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL31164037 | 0.75 | PNMT (0.46) | PNMTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL644951 | 0.74 | PNMT (0.39) | PNMTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL7906609 | 0.74 | PNMT (0.50) | PNMTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL28072512 | 0.74 | PNMT (0.45) | PNMTRAB9ANPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547699-A1 | Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme | MERCK & CO. INC. (US) | 1993-06-23 | — | — | EP | disclosed |