Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280503 | 0.82 | PNMT (0.42) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL28463245 | 0.80 | PNMT (0.51) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL14714715 | 0.77 | RAB9A (0.36) | PNMTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL7906609 | 0.77 | PNMT (0.50) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL7299463 | 0.76 | PNMT (0.41) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL28052119 | 0.76 | PNMT (0.48) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL27960452 | 0.76 | PNMT (0.45) | PNMTRAB9ANPC1HTR7HTR2B | |
| Trifluoroacetic Acid SCHEMBL7518687 | 0.76 | PNMT (0.45) | PNMTRAB9ANPC1HTR7HTR2B | |
| SCHEMBL28918322 | 0.75 | PTPN1 (0.49) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL31632597 | 0.75 | PNMT (0.44) | PNMTRAB9ANPC1HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593068-B | Intermediate of ROR gamma inhibitor and preparation method thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |