Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299922 | 0.85 | DPP4 (0.42) | DPP7DPP8DPP4 | |
| SCHEMBL7299915 | 0.85 | DPP4 (0.42) | DPP7DPP8DPP4 | |
| SCHEMBL7289568 | 0.84 | DPP7 (0.50) | DPP7DPP8KMT2ATP53MAPT | |
| SCHEMBL7289575 | 0.84 | DPP7 (0.50) | DPP7DPP8KMT2ATP53MAPT | |
| Hydrochloric Acid SCHEMBL6763615 | 0.84 | DPP4 (0.42) | DPP7DPP8DPP4 | |
| Hydrochloric Acid SCHEMBL6763608 | 0.84 | DPP4 (0.42) | DPP7DPP8DPP4 | |
| Hydrochloric Acid SCHEMBL6768028 | 0.83 | DPP7 (0.49) | DPP7DPP8KMT2ATP53MAPT | |
| Hydrochloric Acid SCHEMBL6768024 | 0.83 | DPP7 (0.49) | DPP7DPP8KMT2ATP53MAPT | |
| SCHEMBL5712136 | 0.81 | DPP7 (0.41) | DPP7DPP8AKT1FPR2DPP4 | |
| Hydrochloric Acid SCHEMBL6754486 | 0.80 | DPP7 (0.41) | DPP7DPP8FPR2DPP4FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |