Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299915 | 1.00 | DPP4 (0.42) | DPP4DPP7DPP8HDAC8ACACB | |
| Hydrochloric Acid SCHEMBL6763608 | 0.99 | DPP4 (0.42) | DPP4DPP7DPP8HDAC8ACACB | |
| Hydrochloric Acid SCHEMBL6763615 | 0.99 | DPP4 (0.42) | DPP4DPP7DPP8HDAC8ACACB | |
| SCHEMBL7299863 | 0.85 | DPP7 (0.43) | DPP4DPP7DPP8 | |
| SCHEMBL7289568 | 0.81 | DPP7 (0.50) | DPP4DPP7DPP8HDAC8 | |
| SCHEMBL7289575 | 0.81 | DPP7 (0.50) | DPP4DPP7DPP8HDAC8 | |
| Hydrochloric Acid SCHEMBL6768024 | 0.80 | DPP7 (0.49) | DPP4DPP7DPP8HDAC8 | |
| Hydrochloric Acid SCHEMBL6768028 | 0.80 | DPP7 (0.49) | DPP4DPP7DPP8HDAC8 | |
| SCHEMBL7449736 | 0.79 | PRSS1 (0.51) | DPP4DPP7DPP8HDAC8 | |
| SCHEMBL7450368 | 0.79 | PRSS1 (0.51) | DPP4DPP7DPP8HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |