Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6754486 | 0.99 | DPP7 (0.41) | DPP7DPP8DPP9DPP4GAA | |
| Hydrochloric Acid SCHEMBL6678227 | 0.81 | SLC7A5 (0.47) | ALDH1A1HDAC8 | |
| SCHEMBL7299863 | 0.81 | DPP7 (0.43) | DPP7DPP8DPP4FPR2FPR1 | |
| SCHEMBL5712245 | 0.80 | DPP4 (0.68) | DPP7DPP8DPP9DPP4 | |
| SCHEMBL5712137 | 0.80 | DPP7 (0.41) | DPP7DPP8DPP9DPP4GAA | |
| Hydrochloric Acid SCHEMBL6754480 | 0.80 | DPP4 (0.67) | DPP7DPP8DPP9DPP4 | |
| SCHEMBL6676206 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HDAC8 | |
| Hydrochloric Acid SCHEMBL6754491 | 0.79 | DPP7 (0.41) | DPP7DPP8DPP9DPP4GAA | |
| SCHEMBL5712165 | 0.78 | PABPC1 (0.48) | FPR2FPR1HDAC8 | |
| SCHEMBL10885748 | 0.73 | DPP7 (0.42) | DPP7DPP8DPP9DPP4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258476-B1 | Alpha-amino acid derivatives, method for their preparation and their use as dipeptidyl-peptidase IV inhibitors (DPP IV) | SERVIER LAB (FR) | 2006-06-28 | — | — | EP | disclosed |
| EP-1258476-A1 | Alpha-amino acid derivatives, method for their preparation and their use as dipeptidyl-peptidase IV inhibitors (DPP IV) | LES LABORATOIRES SERVIER (FR) | 2002-11-20 | — | — | EP | disclosed |