Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299995 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BFFAR1NPC1RAB9A | |
| SCHEMBL7304069 | 0.94 | FFAR1 (0.41) | ITGB3ITGA2BFFAR1NPC1RAB9A | |
| SCHEMBL7304075 | 0.94 | FFAR1 (0.41) | ITGB3ITGA2BFFAR1NPC1RAB9A | |
| SCHEMBL7298188 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BFFAR1NPC1RAB9A | |
| SCHEMBL7298184 | 0.85 | ITGB3 (0.48) | ITGB3ITGA2BFFAR1NPC1RAB9A | |
| SCHEMBL7308655 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7298306 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7298312 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7308658 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7301234 | 0.79 | ITGB3 (0.36) | ITGB3ITGA2BSMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |