Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304069 | 1.00 | FFAR1 (0.41) | FFAR1ITGB3ITGA2BRXRBNPC1 | |
| SCHEMBL7299995 | 0.94 | ITGB3 (0.47) | FFAR1ITGB3ITGA2BRXRBNPC1 | |
| SCHEMBL7300002 | 0.94 | ITGB3 (0.47) | FFAR1ITGB3ITGA2BRXRBNPC1 | |
| SCHEMBL7300468 | 0.83 | RAB9A (0.44) | FFAR1ITGB3ITGA2BRXRBRAB9A | |
| SCHEMBL7305927 | 0.81 | ITGB3 (0.63) | FFAR1ITGB3ITGA2BRXRB | |
| SCHEMBL7298184 | 0.80 | ITGB3 (0.48) | FFAR1ITGB3ITGA2BRXRBNPC1 | |
| SCHEMBL7298188 | 0.80 | ITGB3 (0.48) | FFAR1ITGB3ITGA2BRXRBNPC1 | |
| SCHEMBL7308655 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7298306 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7308658 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |