Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291203 | 0.92 | MAPT (0.61) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL7299206 | 0.91 | ALDH1A1 (0.67) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL7288759 | 0.89 | ALDH1A1 (0.55) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL7300629 | 0.89 | ALDH1A1 (0.70) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL10720150 | 0.89 | MAPT (0.69) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL10720005 | 0.88 | MAPT (0.64) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL10745338 | 0.86 | MAPT (0.62) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL10717542 | 0.86 | ALDH1A1 (0.62) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL10744872 | 0.86 | MAPT (0.62) | MAPTALDH1A1TSHRNPSR1CYP1A2 | |
| SCHEMBL10717465 | 0.86 | MAPT (0.62) | MAPTALDH1A1TSHRNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | claimed |
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |