Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720116 | 0.92 | LMNA (0.64) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL7299206 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL7300031 | 0.89 | MAPT (0.67) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL7298361 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL7291203 | 0.85 | MAPT (0.61) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL10720150 | 0.85 | MAPT (0.69) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL10720005 | 0.84 | MAPT (0.64) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL7290963 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL29766970 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTTSHRNPSR1TDP1 | |
| SCHEMBL1938827 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTTSHRNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | claimed |
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |