Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506406 | 1.00 | MAOB (0.43) | MAOBGAAGRIN1GRIN2B | |
| SCHEMBL320161 | 0.82 | MAOB (0.45) | MAOBGAA | |
| SCHEMBL3506409 | 0.79 | KDM4E (0.33) | MAOBGAA | |
| SCHEMBL3506404 | 0.79 | KDM4E (0.33) | MAOBGAA | |
| SCHEMBL7298728 | 0.78 | MAOB (0.42) | MAOBGAA | |
| SCHEMBL3505301 | 0.78 | MAOB (0.42) | MAOBGAA | |
| SCHEMBL7297318 | 0.76 | MAOB (0.71) | MAOB | |
| SCHEMBL7302420 | 0.75 | GAA (0.46) | MAOBGAAGRIN1GRIN2B | |
| SCHEMBL9424210 | 0.74 | MAOB (0.57) | MAOB | |
| SCHEMBL3504974 | 0.70 | MAOB (0.41) | MAOBGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655445-B1 | 1,3,4-oxadiazol-2(3H)-one Derivates, their preparation and their use as monoamine oxidase inhibitors | SYNTHELABO (FR) | 1997-08-27 | — | — | EP | claimed |