SCHEMBL9424210

SCHEMBL9424210

COCCn1nc(-c2ccc(OCc3ccc(Cl)cc3)cc2)oc1=O

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.57
NOTUM Q6P988 1/20 0.48
FAAH O00519 1/20 0.47
MGLL Q99685 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7297318 0.89 MAOB (0.71) MAOBFAAHMGLL
SCHEMBL7302420 0.79 GAA (0.46) MAOBNOTUM
SCHEMBL9424213 0.78 S1PR1 (0.47) MAOBNOTUMFAAHMGLL
SCHEMBL320161 0.77 MAOB (0.45) MAOB
SCHEMBL7300033 0.74 MAOB (0.43) MAOB
SCHEMBL7298728 0.74 MAOB (0.42) MAOB
SCHEMBL9424127 0.73 MAOB (0.57) MAOB
SCHEMBL202570 0.72 MAOB (1.00) MAOB
SCHEMBL9424025 0.72 DHFR (0.42) MAOB
SCHEMBL12377828 0.69 GRIN1 (0.46) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5376648-A Inhibit type B monoamine oxidase DELALANDE S.A. (FR) 1994-12-27 US claimed