Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424210 | 0.79 | MAOB (0.57) | MAOBNOTUM | |
| SCHEMBL12377828 | 0.77 | GRIN1 (0.46) | GAANOTUMGRIN1GRIN2B | |
| SCHEMBL7298728 | 0.76 | MAOB (0.42) | GAAMAOB | |
| SCHEMBL7300033 | 0.75 | MAOB (0.43) | GAAMAOBGRIN1GRIN2B | |
| SCHEMBL13863022 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL7302416 | 0.70 | NOTUM (0.40) | GAANOTUM | |
| SCHEMBL11857867 | 0.68 | FAAH (0.46) | — | |
| SCHEMBL10703697 | 0.65 | KDM4E (0.51) | GAAMAOBGRIN1GRIN2B | |
| SCHEMBL11869259 | 0.64 | TDP1 (0.44) | GAA | |
| SCHEMBL10437798 | 0.64 | MAOB (0.46) | GAAMAOBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655445-B1 | 1,3,4-oxadiazol-2(3H)-one Derivates, their preparation and their use as monoamine oxidase inhibitors | SYNTHELABO (FR) | 1997-08-27 | — | — | EP | disclosed |
| US-5525619-A | INHIBITORS OF MONOAMINE OXIDASE B | SYNTHELABO (FR) | 1996-06-11 | — | — | US | disclosed |
| EP-0655445-A1 | 1,3,4-oxadiazol-2(3H)-one Derivates, their preparation and their use as monoamine oxidase inhibitors | SYNTHELABO (FR) | 1995-05-31 | — | — | EP | disclosed |