Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583946 | 0.87 | DAO (0.33) | BACE1CTSDTRPV1TP53LMNA | |
| SCHEMBL7294955 | 0.78 | HTR2C (0.42) | TP53 | |
| SCHEMBL7301080 | 0.77 | PTGS1 (0.39) | PTGS1PTGS2BACE1CTSDTRPV1 | |
| SCHEMBL7293466 | 0.76 | KDM4E (0.34) | TP53CA12CA9 | |
| SCHEMBL7134096 | 0.75 | MAPT (0.49) | PTGS1PTGS2TP53LMNAOPRM1 | |
| SCHEMBL2350567 | 0.75 | BACE1 (0.36) | BACE1CTSDLMNACA12CA9 | |
| SCHEMBL7294557 | 0.75 | HTR2C (0.42) | BACE1CTSDCA12CA9 | |
| SCHEMBL2351278 | 0.72 | HPGD (0.32) | PTGS1LMNA | |
| SCHEMBL7766906 | 0.72 | ALDH1A1 (0.42) | PTGS1PTGS2TP53CA12CA9 | |
| SCHEMBL7292949 | 0.71 | ABCB1 (0.40) | LMNACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |