SCHEMBL7300183

SCHEMBL7300183

N=C1OCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28382077 0.55
SCHEMBL7946945 0.55
SCHEMBL744061 0.55
SCHEMBL12643175 0.55
SCHEMBL1332032 0.55
SCHEMBL2011229 0.55
SCHEMBL16197636 0.55 LMNA (0.47)
SCHEMBL186519 0.55
SCHEMBL20546841 0.55 ALDH1A1 (0.47)
SCHEMBL30368594 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025045680-A1 METHOD TO MAKE BICYCLIC GUANIDINES EVONIK OPERATIONS GMBH (DE) 2025-03-06 WO claimed
EP-0435843-B1 Substituted pyridine compounds MONSANTO CO (US) 1994-06-15 EP claimed
US-5129943-A Herbicides MONSANTO COMPANY (US) 1992-07-14 US claimed
US-5112980-A Intermediates for herbicides MONSANTO COMPANY (US) 1992-05-12 US claimed
EP-0435844-A1 Substituted pyridine compounds MONSANTO COMPANY (US) 1991-07-03 EP claimed
EP-0435843-A1 Substituted pyridine compounds MONSANTO COMPANY (US) 1991-07-03 EP claimed
JP-2311481-A None JP disclosed
WO-2025045680-A1 METHOD TO MAKE BICYCLIC GUANIDINES EVONIK OPERATIONS GMBH (DE) 2025-03-06 WO disclosed
US-20150119356-A1 Ophthalmic Viscoelastic Device CARL ZEISS MEDITEC AG (DE) 2015-04-30 US disclosed
EP-0435843-B1 Substituted pyridine compounds MONSANTO CO (US) 1994-06-15 EP disclosed
EP-0413516-B1 4-Methylene-1-oxa-2-oxo-8-azaspiro[4,5]decane derivatives, pharmaceutical compositions containing them and processes for preparing them RICHTER GEDEON VEGYESZET (HU) 1994-04-20 EP disclosed
EP-0414422-B1 2-Oxo-1-oxa-8-azaspiro [4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof RICHTER GEDEON VEGYESZET (HU) 1994-04-06 EP disclosed
EP-0414421-B1 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof RICHTER GEDEON VEGYESZET (HU) 1994-04-06 EP disclosed
EP-0435844-A1 Substituted pyridine compounds MONSANTO COMPANY (US) 1991-07-03 EP disclosed
EP-0435843-A1 Substituted pyridine compounds MONSANTO COMPANY (US) 1991-07-03 EP disclosed
EP-0414421-A2 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1991-02-27 EP disclosed
EP-0414422-A2 2-Oxo-1-oxa-8-azaspiro [4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1991-02-27 EP disclosed
EP-0413516-A2 4-Methylene-1-oxa-2-oxo-8-azaspiro[4,5]decane derivatives, pharmaceutical compositions containing them and processes for preparing them RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1991-02-20 EP disclosed
EP-0412820-A2 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1991-02-13 EP disclosed
JP-H02311481-A 1,4,6-TRIOXA-9-AZASPIRO(4,4)NONANE DERIVATIVE AND ITS PRODUCTION NIPPON PAINT CO LTD 1990-12-27 JP disclosed