Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294182 | 0.72 | ITGB2 (0.39) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL7128137 | 0.72 | ITGB2 (0.44) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL7290576 | 0.72 | ITGB2 (0.39) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL14304553 | 0.72 | ITGB2 (0.39) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL7290867 | 0.72 | ITGB2 (0.39) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL9584132 | 0.72 | MAP3K14 (0.44) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL7301413 | 0.71 | TRPA1 (0.40) | TRPA1TSHRKDM4EALDH1A1CA1 | |
| SCHEMBL27612514 | 0.71 | CYP2B6 (0.40) | TRPA1TSHRKDM4EALDH1A1CA1 | |
| SCHEMBL21224311 | 0.69 | ITGB2 (0.37) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL30289551 | 0.69 | ITGB2 (0.37) | ITGB2ICAM1ITGALNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |