Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299195 | 0.73 | HTR2C (0.36) | — | |
| SCHEMBL7298266 | 0.72 | NOTUM (0.38) | — | |
| SCHEMBL7288885 | 0.72 | HTR2C (0.35) | ALDH1A1CA1CA2 | |
| SCHEMBL7128137 | 0.72 | ITGB2 (0.44) | TRPA1KDM4E | |
| SCHEMBL7300186 | 0.71 | ITGB2 (0.35) | TRPA1TSHRKDM4EALDH1A1CA1 | |
| SCHEMBL3188143 | 0.70 | PARP1 (0.47) | TRPA1TSHRKDM4EALDH1A1 | |
| SCHEMBL9506555 | 0.69 | TRPA1 (0.40) | TRPA1TSHRKDM4EALDH1A1CA1 | |
| SCHEMBL7292475 | 0.68 | TRPA1 (0.37) | TRPA1TSHR | |
| SCHEMBL4695076 | 0.68 | PARP1 (0.38) | TRPA1TSHRKDM4EALDH1A1 | |
| SCHEMBL9584581 | 0.68 | KMT2A (0.43) | KDM4EALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |