Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.69 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305898 | 0.83 | SIGMAR1 (0.77) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL7294524 | 0.82 | SIGMAR1 (0.76) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL7299921 | 0.82 | SIGMAR1 (1.00) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL7299989 | 0.81 | SIGMAR1 (0.75) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL17237763 | 0.81 | SIGMAR1 (0.75) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL7298240 | 0.81 | SIGMAR1 (0.75) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL3605597 | 0.80 | SIGMAR1 (0.76) | SIGMAR1CYP11B1CYP11B2PPARGHTR1A | |
| SCHEMBL7308430 | 0.79 | SIGMAR1 (0.71) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL7297159 | 0.78 | SIGMAR1 (0.81) | SIGMAR1CYP11B1CYP11B2PPARGACHE | |
| SCHEMBL7302267 | 0.78 | SIGMAR1 (0.71) | SIGMAR1CYP11B1CYP11B2PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | claimed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | claimed |