⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093132 | 1.00 | — | — | |
| SCHEMBL29386319 | 1.00 | — | — | |
| SCHEMBL8710 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6762162 | 0.97 | MAOA (0.42) | — | |
| Ammonia Solution, Strong SCHEMBL3205764 | 0.97 | MAOA (0.42) | — | |
| SCHEMBL3682309 | 0.97 | MAOA (0.42) | — | |
| Methane SCHEMBL10528050 | 0.97 | MAOA (0.42) | — | |
| SCHEMBL181520 | 0.91 | MAOA (0.38) | — | |
| SCHEMBL7234494 | 0.89 | ABCG2 (0.58) | — | |
| Piperazine SCHEMBL5564115 | 0.89 | HTR2C (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107623-A2 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | claimed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | claimed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | claimed |
| US-4346228-A | Novel 11-oxoprostaglandin derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | claimed |
| US-4088775-A | PROSTAGLANDINS WITH LONG LASTING ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | claimed |
| WO-2023107623-A2 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-8557860-B2 | Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents | ALLERGAN, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| EP-1666473-B1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8168680-B2 | Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents | ALLERGAN, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-2331533-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| US-20110130439-A1 | CYCLOPENTANE HEPTAN(ENE)OIC ACID, 2-HETEROARYLALKENYL DERIVATIVES AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2006022974-A1 | 2-HETEROARYLALKENYLCYCLOPENTANE HEPTAN - (ENE) - OIC ACID DERIVATIVES AS THERAPEUTC AGENTS | ALLERGAN, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006020510-A1 | CYCLOPENTANE HEPTAN(ENE)OIC ACID, 2-HETEROARYLALKENYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN RECEPTOR MODULATORS | ALLERGAN INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060035960-A1 | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents | ALLERGAN, INC. (US) | 2006-02-16 | — | — | US | disclosed |
| US-20060035949-A1 | Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents | ALLERGAN, INC. (US) | 2006-02-16 | — | — | US | disclosed |
| US-4346228-A | Novel 11-oxoprostaglandin derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | disclosed |
| US-4346228-A | Novel 11-oxoprostaglandin derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | disclosed |