Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9288787 | 0.81 | POLB (0.43) | POLBCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL20345576 | 0.81 | SLC22A12 (0.39) | POLBCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL21818566 | 0.79 | NOTUM (0.36) | POLBCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL5875543 | 0.76 | MAPK14 (0.57) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL21586242 | 0.74 | ALKBH1 (0.46) | POLBCYP1A2MEN1KMT2AL3MBTL1 | |
| SCHEMBL19327459 | 0.74 | MAPK14 (0.40) | POLBCYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL14592079 | 0.73 | CSF1R (0.48) | POLBMEN1KMT2AKDM4EHPGD | |
| SCHEMBL951965 | 0.72 | MEN1 (0.51) | POLBCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL16447824 | 0.72 | PTGER1 (0.41) | POLBKDM4EMAPT | |
| SCHEMBL20669578 | 0.71 | DYRK1A (0.43) | POLBCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200415-A | Serotonin receptor antagonists; antiemetics, antianxietics | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0483836-A1 | Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-05-06 | — | — | EP | disclosed |