Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998950 | 0.91 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL6685168 | 0.91 | ITGB3 (0.79) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL18764418 | 0.89 | ITGB3 (0.78) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL23302994 | 0.88 | ITGB3 (0.76) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL23302993 | 0.88 | ITGB3 (0.76) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL7330647 | 0.87 | ITGB3 (0.74) | ITGB3ITGA2BPTPN1ACE | |
| SCHEMBL7291406 | 0.87 | ITGB3 (0.82) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL7335757 | 0.87 | ITGB3 (0.74) | ITGB3ITGA2BPTPN1ACE | |
| SCHEMBL13367280 | 0.87 | ITGB3 (0.74) | ITGB3ITGA2BPTPN1ACEHDAC8 | |
| SCHEMBL14937759 | 0.87 | ITGB3 (0.74) | ITGB3ITGA2BPTPN1ACEHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |