Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 5/20 | 0.40 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300344 | 1.00 | FOLH1 (0.46) | FOLH1ALDH1A1RENMEN1LMNA | |
| SCHEMBL4300867 | 0.89 | NOD1 (0.44) | FOLH1KMT2ABMP1 | |
| SCHEMBL29564468 | 0.88 | FOLH1 (0.50) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1674751 | 0.88 | ALDH1A1 (0.53) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1674750 | 0.88 | ALDH1A1 (0.53) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL18613505 | 0.88 | ALDH1A1 (0.53) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL31073601 | 0.88 | GRIN2D (0.47) | FOLH1ALDH1A1BMP1BACE1TASP1 | |
| SCHEMBL29638079 | 0.87 | ECE1 (0.44) | RENBMP1BACE1 | |
| SCHEMBL29425348 | 0.86 | ALDH1A1 (0.49) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL30546210 | 0.86 | FOLH1 (0.55) | FOLH1BMP1BACE1TASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316769-A2 | Disulfide bridged cyclic peptides containing a cgridri sequence useful in control of hypertension | G.D. Searle & Co. (US) | 1989-05-24 | — | — | EP | claimed |
| EP-0316769-A2 | Disulfide bridged cyclic peptides containing a cgridri sequence useful in control of hypertension | G.D. Searle & Co. (US) | 1989-05-24 | — | — | EP | disclosed |