Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447508 | 0.88 | CTSK (0.54) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL6447502 | 0.88 | CTSK (0.54) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL24049431 | 0.78 | PSMB5 (0.53) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL7264560 | 0.77 | CTSK (0.53) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL7264559 | 0.77 | CTSK (0.53) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL8365044 | 0.76 | CTSK (0.55) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL1861195 | 0.76 | CTSK (0.55) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL1861194 | 0.76 | CTSK (0.55) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL7292249 | 0.75 | LTA4H (0.38) | CTSKCTSLCTSBPSMB5REN | |
| SCHEMBL14996241 | 0.75 | CA1 (0.56) | CTSKCTSSCTSLCTSBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605926-A | PROPHYLAXIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5430151-A | Treatment of aids, pneumonia, caprine arthritis encephalitis, leukemia and immmunodeficiency | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| EP-0528242-A2 | Trifluoromethyl containing pseudopeptides | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |