Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | DHODH | Q02127 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DHPS | P49366 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14859607 | 0.88 | L3MBTL1 (0.53) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8522419 | 0.85 | L3MBTL1 (0.72) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6054998 | 0.84 | L3MBTL1 (0.76) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10863434 | 0.83 | L3MBTL1 (0.71) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14859608 | 0.83 | L3MBTL1 (0.48) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13716209 | 0.83 | L3MBTL1 (0.59) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10114514 | 0.82 | L3MBTL1 (0.58) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28987534 | 0.81 | L3MBTL1 (0.72) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13676193 | 0.81 | ALDH1A1 (0.65) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13675870 | 0.80 | TRPV1 (0.61) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |