Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7373367 | 0.89 | MMP2 (0.54) | MMP2HPGDALDH1A1KMT2ASLC6A2 | |
| SCHEMBL23978690 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL7299215 | 0.82 | MMP2 (0.55) | MMP2HPGDALDH1A1KMT2ASLC6A2 | |
| SCHEMBL7301216 | 0.80 | SYK (0.55) | KMT2ATDP1HTTLMNASMN1; SMN2 | |
| SCHEMBL7872542 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL27690076 | 0.79 | ALDH1A1 (0.53) | HPGDALDH1A1KMT2ASLC6A2SLC6A3 | |
| Zinc Ion SCHEMBL6051916 | 0.79 | MMP2 (0.51) | MMP2HPGDKMT2ASLC6A2SLC6A3 | |
| SCHEMBL7350146 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL7368912 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL7368915 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |