Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.66 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.59 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826987 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| Tiropramide SCHEMBL25693 | 0.89 | LMNA (0.54) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| SCHEMBL11778188 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| Tiropramide SCHEMBL2255455 | 0.88 | LMNA (0.53) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| Tiropramide SCHEMBL25414231 | 0.87 | LMNA (0.53) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| Tiropramide SCHEMBL25414380 | 0.87 | LMNA (0.53) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| SCHEMBL11782109 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| SCHEMBL22604666 | 0.85 | GAA (0.73) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| SCHEMBL1123050 | 0.84 | PTPN1 (0.69) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| SCHEMBL11780603 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BITGB1ITGAVITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | disclosed |