Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 13/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182263 | 0.87 | NR1H4 (0.76) | NR1H4SMN1; SMN2LMNAMAPT | |
| SCHEMBL4659050 | 0.85 | NR1H4 (0.74) | NR1H4SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL7303163 | 0.85 | HDAC3 (0.86) | NR1H4SMN1; SMN2LMNAMAPTHDAC3 | |
| SCHEMBL10685426 | 0.84 | NR1H4 (0.73) | NR1H4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7301317 | 0.84 | NR1H4 (0.73) | NR1H4SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL840854 | 0.83 | NR1H4 (0.70) | NR1H4SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL3873116 | 0.82 | NR1H4 (0.81) | NR1H4SMN1; SMN2EPHX2HDAC3HDAC11 | |
| SCHEMBL8143801 | 0.82 | NR1H4 (0.82) | NR1H4NPC1RAB9A | |
| SCHEMBL7297239 | 0.82 | NR1H4 (0.81) | NR1H4SMN1; SMN2EPHX2HDAC3HDAC11 | |
| Methane SCHEMBL17237476 | 0.82 | NR1H4 (0.68) | NR1H4SMN1; SMN2LMNAMAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |