Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566157 | 0.89 | SIRT1 (0.62) | NR1H4SMN1; SMN2MAPTLMNAHDAC3 | |
| SCHEMBL7303163 | 0.88 | HDAC3 (0.86) | NR1H4SMN1; SMN2MAPTLMNAHDAC3 | |
| SCHEMBL12264103 | 0.87 | RAB9A (0.65) | NR1H4SMN1; SMN2MAPTLMNATRPV1 | |
| SCHEMBL7302615 | 0.85 | NR1H4 (0.76) | NR1H4SMN1; SMN2MAPTLMNAHDAC3 | |
| SCHEMBL7300696 | 0.84 | NR1H4 (1.00) | NR1H4SMN1; SMN2MAPTLMNAHDAC3 | |
| SCHEMBL13762077 | 0.84 | HDAC3 (0.69) | NR1H4SMN1; SMN2MAPTLMNAHDAC3 | |
| SCHEMBL16607007 | 0.83 | ALDH1A1 (0.69) | NR1H4SMN1; SMN2LMNATRPV1RAB9A | |
| SCHEMBL5380043 | 0.83 | HDAC6 (0.63) | SMN1; SMN2MAPTHDAC3HDAC11HDAC8 | |
| SCHEMBL8361567 | 0.83 | NPC1 (0.76) | SMN1; SMN2MAPTLMNATRPV1RAB9A | |
| SCHEMBL16610194 | 0.83 | DEGS1 (0.61) | SMN1; SMN2MAPTLMNATRPV1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |