Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.58 |
| ▸ | FAP | Q12884 | 5/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.58 |
| ▸ | PREP | P48147 | 3/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.58 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031886 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL14235325 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL22673059 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL2031883 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL7994236 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| Hydrochloric Acid SCHEMBL11211318 | 0.98 | DPP4 (0.57) | DPP4DPP7FAPDPP8PREP | |
| Trifluoroacetic Acid SCHEMBL26616483 | 0.89 | DPP4 (0.49) | DPP4DPP7FAPDPP8PREP | |
| Trifluoroacetic Acid SCHEMBL31376322 | 0.89 | DPP4 (0.49) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL10311685 | 0.87 | ACE (0.49) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL5950374 | 0.87 | ACE (0.49) | DPP4DPP7FAPDPP8PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677531-A1 | Derivates of boronic peptides, preparation and use thereof in therapy | SYNTHELABO (FR) | 1995-10-18 | — | — | EP | disclosed |