Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.49 |
| ▸ | FAP | Q12884 | 3/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 6/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | PEPD | P12955 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26616483 | 1.00 | DPP4 (0.49) | DPP4FAPDPP7DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL10784297 | 0.90 | ACE (0.55) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL7300736 | 0.89 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL2031886 | 0.89 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL22673059 | 0.89 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL2031883 | 0.89 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL7994236 | 0.89 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL14235325 | 0.89 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL11211318 | 0.88 | DPP4 (0.57) | DPP4FAPDPP7DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL9508365 | 0.85 | DPP4 (0.54) | DPP4DPP7DPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451944-A | PREP binding ligands | 珀尔库治疗有限公司 | 2025-02-14 | — | — | CN | disclosed |