Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.58 |
| ▸ | FAP | Q12884 | 5/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.58 |
| ▸ | PREP | P48147 | 3/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.58 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031886 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL14235325 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL22673059 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL7300736 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL7994236 | 1.00 | DPP4 (0.58) | DPP4DPP7FAPDPP8PREP | |
| Hydrochloric Acid SCHEMBL11211318 | 0.98 | DPP4 (0.57) | DPP4DPP7FAPDPP8PREP | |
| Trifluoroacetic Acid SCHEMBL26616483 | 0.89 | DPP4 (0.49) | DPP4DPP7FAPDPP8PREP | |
| Trifluoroacetic Acid SCHEMBL31376322 | 0.89 | DPP4 (0.49) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL10311685 | 0.87 | ACE (0.49) | DPP4DPP7FAPDPP8PREP | |
| SCHEMBL5950374 | 0.87 | ACE (0.49) | DPP4DPP7FAPDPP8PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250288559-A1 | PREP BINDING LIGANDS | POLKU THERAPEUTICS OY (FI) | 2025-09-18 | — | — | US | disclosed |
| EP-4514781-A1 | PREP BINDING LIGANDS | Polku Therapeutics OY (FI) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |
| US-20210000843-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2021-01-07 | — | — | US | disclosed |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2019-08-29 | — | — | US | disclosed |
| US-9884070-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-02-06 | — | — | US | disclosed |
| US-20180008622-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-01-11 | — | — | US | disclosed |
| US-20110144065-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | U.S. DEPARTMENT OF ENERGY | 2011-06-16 | — | — | US | disclosed |
| CN-1113493-A | Boron containing derivative and preparation and medical application of same | SYNTHELABO (FR) | 1995-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | DPP4 3126/4885DPP7 2903/4885FAP 3032/4885 |
| US-20110144065-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | DPP4 3126/4885DPP7 2903/4885FAP 3032/4885 |
| US-20180008622-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | DPP4 3126/4885DPP7 2903/4885FAP 3032/4885 |
| US-20250288559-A1 | PREP BINDING LIGANDS | PREP, ERAP2, CTSA | DPP4 101/4885DPP7 69/4885FAP 49/4885 |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | DPP4 3126/4885DPP7 2903/4885FAP 3032/4885 |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | DPP4 3126/4885DPP7 2903/4885FAP 3032/4885 |
| US-20210000843-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | DPP4 3126/4885DPP7 2903/4885FAP 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.