Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 7/20 | 0.56 |
| ▸ | CTSS | P25774 | 6/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310119 | 1.00 | CTRB1 (0.61) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL4598612 | 1.00 | CTRB1 (0.61) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL7288504 | 0.94 | CTSL (0.56) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL10724398 | 0.94 | CTSL (0.56) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL10724038 | 0.92 | CTRB1 (0.53) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL10724041 | 0.92 | CTRB1 (0.53) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL11669304 | 0.90 | CTSL (0.63) | CTRB1TACR1CTSLCTSSCTSK | |
| SCHEMBL10720521 | 0.89 | TACR1 (0.67) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL10720515 | 0.89 | TACR1 (0.67) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL10720700 | 0.88 | CYP3A4 (0.56) | CTRB1TACR1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650785-A | ORAL ADMINISTRATION OF INSULIN | AJINOMOTO COMPANY INCOPORATED (JP) | 1987-03-17 | — | — | US | claimed |
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | claimed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | claimed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | claimed |
| JP-58189121-A | — | — | None | — | — | JP | disclosed |
| JP-62026273-A | — | — | None | — | — | JP | disclosed |
| CN-1092960-C | Pharmaceutical composition containing protease inhibitor and monoglyceride | HOFFMANN LA ROCHE (US) | 2002-10-23 | — | — | CN | disclosed |
| US-6008228-A | COMPRISING A MIXTURE OF CARRIER MONOGLYCERIDES OF MEDIUM CHAIN-FATTY ACIDS | HOFFMAN-LA ROCHE INC. (US) | 1999-12-28 | — | — | US | disclosed |
| CN-1186434-A | Pharmaceutical composition containing protease inhibitor and monoglyceride | HOFFMANN LA ROCHE (US) | 1998-07-01 | — | — | CN | disclosed |
| EP-0594540-B1 | Antiretroviral acyl compounds | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| EP-0831826-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039142-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-12 | — | — | WO | disclosed |
| JP-S6226273-A | ISOQUINOLINE DERIVATIVE AND USE THEREOF | AJINOMOTO CO INC | 1987-02-04 | — | — | JP | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | disclosed |
| EP-0093551-A2 | Pharmaceutical composition | AJINOMOTO CO., INC. (JP) | 1983-11-09 | — | — | EP | disclosed |
| JP-S58189121-A | ACTIVATOR FOR ADMINISTRATION OF INSULIN | AJINOMOTO CO INC | 1983-11-04 | — | — | JP | disclosed |