Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995249 | 0.79 | SMN1; SMN2 (0.37) | TSHRSMN1; SMN2CA1CA2CA14 | |
| SCHEMBL1398170 | 0.79 | CA1 (0.38) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL23302295 | 0.78 | MGAM (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3525495 | 0.77 | CA1 (0.37) | TSHRSMN1; SMN2CA1CA2CA14 | |
| SCHEMBL453120 | 0.77 | SMN1; SMN2 (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL628847 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27964975 | 0.75 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7766666 | 0.74 | TSHR (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5143415 | 0.74 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2576619 | 0.74 | GAA (0.56) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182402-A | 2-Phenylthiazolecarboxylic Acids and Esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-26 | — | — | US | disclosed |
| US-5084083-A | Phenylthiazolecarboxylic acid derivative herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| CN-1042907-A | Herbicidal composition | ICI PLC (GB) | 1990-06-13 | — | — | CN | disclosed |
| EP-0368592-A1 | Herbicidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-16 | — | — | EP | disclosed |
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |