SCHEMBL1398170

SCHEMBL1398170

CCC(=O)C(Cl)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CYP2C9 P11712 1/20 0.37
ZDHHC7 Q9NXF8 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
CA14 Q9ULX7 2/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
CA12 O43570 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1597955 0.81 SOAT1 (0.44) CYP2C9MGAMGAASIMGAM2
SCHEMBL19995249 0.81 SMN1; SMN2 (0.37) CA1CA2SMN1; SMN2ZDHHC7CA14
SCHEMBL3525495 0.79 CA1 (0.37) CA1CA2SMN1; SMN2ZDHHC7CA14
SCHEMBL7300819 0.79 MGAM (0.42) CA1CA2SMN1; SMN2ZDHHC7MGAM
SCHEMBL453120 0.79 SMN1; SMN2 (0.50) CA1CA2SMN1; SMN2ZDHHC7MGAM
SCHEMBL509870 0.79 CYP2C9 (0.40) CYP2C9SOAT1ALDH1A1TSHR
SCHEMBL1554465 0.79 CA1 (0.46) CA1CA2ZDHHC7ALDH1A1KMT2A
SCHEMBL18098644 0.76 MGAM (0.44) CA1CA2SMN1; SMN2ZDHHC7MGAM
SCHEMBL14800513 0.76 CES2 (0.50) ZDHHC7ALDH1A1TSHRKMT2A
SCHEMBL9834673 0.76 CES2 (0.50) ZDHHC7ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121575055-A Method for efficiently synthesizing 2-chloro-3-oxopentanoic acid methyl ester 内蒙古华洲药业有限公司 2026-02-27 CN claimed
CN-111217758-A Preparation method of 6-ethyl-5-fluoro-4-chloropyrimidine 湖南复瑞生物医药技术有限责任公司 2020-06-02 CN claimed
CN-122029166-A Condensed cyclic compound and harmful arthropod control composition containing the same 住友化学株式会社 2026-05-12 CN disclosed
CN-121575055-A Method for efficiently synthesizing 2-chloro-3-oxopentanoic acid methyl ester 内蒙古华洲药业有限公司 2026-02-27 CN disclosed
CN-121575055-A Method for efficiently synthesizing 2-chloro-3-oxopentanoic acid methyl ester 内蒙古华洲药业有限公司 2026-02-27 CN disclosed
CN-121575055-A Method for efficiently synthesizing 2-chloro-3-oxopentanoic acid methyl ester 内蒙古华洲药业有限公司 2026-02-27 CN disclosed
EP-4619104-A1 BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS Novartis AG (CH) 2025-09-24 EP disclosed
EP-4601746-A1 TRICYCLIC COMPOUNDS AND THEIR USES Novartis AG (CH) 2025-08-20 EP disclosed
EP-4570313-A2 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2025-06-18 EP disclosed
CN-120077048-A Tricyclic compounds and uses thereof 诺华股份有限公司 2025-05-30 CN disclosed
CN-120040475-A Compounds as WRN inhibitors and uses thereof 南京圣和药业股份有限公司 2025-05-27 CN disclosed
EP-0708758-B1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED HOECHST SCHERING AGREVO GMBH (DE) 1998-02-04 EP disclosed
EP-0761642-A2 Process for preparing 2-amino-1, 3-alkanediol or a derivative thereof, process for preparing optically active dihydrosphingosine derivatives and intermediates used in that process Takasago International Corporation (JP) 1997-03-12 EP disclosed
US-5523404-A Process for preparing 5-chloro-4-hydroxypyrimidines HOECHST SCHERING AGREVO GMBH (DE) 1996-06-04 US disclosed
EP-0708758-A1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED Hoechst Schering AgrEvo GmbH (DE) 1996-05-01 EP disclosed
WO-1995001963-A1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED HOECHST SCHERING AGREVO GMBH (DE) 1995-01-19 WO disclosed
EP-0370391-B1 Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine LONZA AG (CH) 1994-11-02 EP disclosed
WO-1992006965-A1 HERBICIDAL SULFONYLUREA DERIVATIVES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1992-04-30 WO disclosed
US-4977264-A Condensing 2-chloro-3-oxo-pentanoic acid ester with formamidinium salt, reacting with phosphoryl chloride LONZA LTD. (CH) 1990-12-11 US disclosed
EP-0370391-A2 Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine LONZA AG (CH) 1990-05-30 EP disclosed