Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | MITF | O75030 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296723 | 1.00 | RAB9A (0.71) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL1687869 | 1.00 | RAB9A (0.71) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL23898948 | 0.89 | KMT2A (0.83) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL9134339 | 0.89 | KMT2A (0.83) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL8572381 | 0.89 | KMT2A (0.83) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL2350357 | 0.86 | MAPT (0.77) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL15149939 | 0.86 | MAPT (0.55) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL7303163 | 0.85 | HDAC3 (0.86) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL11972898 | 0.85 | RAB9A (0.68) | RAB9AMAPTNPC1KMT2AMEN1 | |
| SCHEMBL13428706 | 0.85 | RAB9A (0.68) | RAB9AMAPTNPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |