Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | MITF | O75030 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.63 |
| ▸ | RORC | P51449 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11972898 | 1.00 | RAB9A (0.68) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL23898948 | 0.89 | KMT2A (0.83) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL9134339 | 0.89 | KMT2A (0.83) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL8572381 | 0.89 | KMT2A (0.83) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL31151527 | 0.88 | MEN1 (0.68) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL28217527 | 0.88 | P2RX1 (0.68) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL28330879 | 0.88 | MEN1 (0.68) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL6301913 | 0.88 | MEN1 (0.74) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL5314484 | 0.87 | RORC (0.69) | RAB9AMEN1KMT2ANPC1MITF | |
| SCHEMBL11973033 | 0.85 | ABCG2 (0.53) | RAB9AMEN1KMT2ANPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069443-A1 | COMPOUND WITH BENZAMIDE SKELETON HAVING CYCLOOXYGENASE-1 (COX-1)-SELECTIVE INHIBITORY ACTIVITY | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069443-A1 | COMPOUND WITH BENZAMIDE SKELETON HAVING CYCLOOXYGENASE-1 (COX-1)-SELECTIVE INHIBITORY ACTIVITY | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2070908-A1 | COMPOUND HAVING BENZAMIDE SKELETON AND CYCLOOXYGENASE (COX-1)-SELECTIVE INHIBITORY ACTIVITY | National University Corporation Okayama University (JP) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069443-A1 | COMPOUND WITH BENZAMIDE SKELETON HAVING CYCLOOXYGENASE-1 (COX-1)-SELECTIVE INHIBITORY ACTIVITY | PTGS1, PTGS2, PTGIS | RAB9A 3360/4885MEN1 2531/4885KMT2A 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.