Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.60 |
| ▸ | MAOB | P27338 | 8/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294747 | 0.90 | MAOB (0.59) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL7301295 | 0.86 | ACHE (0.62) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL7294118 | 0.82 | ALDH1A1 (0.57) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL7301316 | 0.82 | MAOB (0.59) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL7302328 | 0.81 | ACHE (0.56) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL7296704 | 0.80 | MAOB (0.55) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL5617782 | 0.80 | ALDH1A1 (0.58) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL7298181 | 0.80 | ACHE (0.64) | ACHEMAOBMAOAPOLBRAB9A | |
| SCHEMBL7303830 | 0.80 | ACHE (0.55) | ACHEMAOBMAOAALDH1A1POLB | |
| SCHEMBL5812887 | 0.79 | ALDH1A1 (0.54) | ACHEMAOBMAOAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |