SCHEMBL7300856

SCHEMBL7300856

Cc1cccc2c(C(=O)N[C@H]3CN4CCC3CC4)cnn12

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7309664 1.00 CHRNA7 (0.56) CHRNA7
SCHEMBL7300863 1.00 CHRNA7 (0.56) CHRNA7
SCHEMBL7307817 0.87 HTR3A (0.51)
SCHEMBL7300575 0.85 HTR3A (0.52)
SCHEMBL7298701 0.81 KDM4E (0.54) CHRNA7
SCHEMBL7302291 0.81 CHRNA7 (0.55) CHRNA7
Hydrochloric Acid SCHEMBL7302181 0.81 KDM4E (0.53)
SCHEMBL7300781 0.80 CHRNA7 (0.52) CHRNA7
SCHEMBL7301800 0.79 JAK2 (0.53) CHRNA7
SCHEMBL7306336 0.78 CHRNA7 (0.50) CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5200415-A Serotonin receptor antagonists; antiemetics, antianxietics ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-04-06 US disclosed
EP-0483836-A1 Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-05-06 EP disclosed