SCHEMBL7307817

SCHEMBL7307817

CCc1cccc2c(C(=O)NC3CN4CCC3CC4)cnn12

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7300575 0.92 HTR3A (0.52) HTR3A
SCHEMBL7300863 0.87 CHRNA7 (0.56)
SCHEMBL7300856 0.87 CHRNA7 (0.56)
SCHEMBL7309664 0.87 CHRNA7 (0.56)
SCHEMBL7299594 0.79 CHRNA7 (0.47) HTR3A
SCHEMBL7298701 0.78 KDM4E (0.54)
Hydrochloric Acid SCHEMBL7302181 0.77 KDM4E (0.53)
SCHEMBL9531570 0.77 CHRNA7 (0.52)
SCHEMBL7447481 0.75 HTR3A (0.56) HTR3A
SCHEMBL7447489 0.75 HTR3A (0.56) HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5200415-A Serotonin receptor antagonists; antiemetics, antianxietics ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-04-06 US claimed
EP-0483836-A1 Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-05-06 EP claimed