Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30812977 | 0.84 | POLB (0.44) | SSTR4MAPK1GAASMN1; SMN2TRPV1 | |
| SCHEMBL9785817 | 0.84 | POLB (0.44) | SSTR4MAPK1GAASMN1; SMN2TRPV1 | |
| SCHEMBL27720908 | 0.84 | SSTR4 (0.40) | SSTR4MAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21798462 | 0.81 | SSTR4 (0.41) | SSTR4MAPK1GAASMN1; SMN2TRPV1 | |
| SCHEMBL24262284 | 0.80 | SSTR4 (0.38) | SSTR4MAPK1CYP1A2CYP2C19GAA | |
| SCHEMBL29208044 | 0.77 | SSTR4 (0.46) | SSTR4MAPK1TRPV1BRD4CREBBP | |
| SCHEMBL623491 | 0.76 | POLB (0.43) | SSTR4CYP1A2CYP2C19GAA | |
| SCHEMBL2740802 | 0.76 | SSTR4 (0.41) | SSTR4MAPK1GAAHTR2A | |
| SCHEMBL7297689 | 0.76 | TRPV1 (0.39) | MAPK1CYP2C9CYP2C19GAATRPV1 | |
| SCHEMBL624499 | 0.76 | PTGDR2 (0.40) | SSTR4CNR1CNR2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |