Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785817 | 1.00 | POLB (0.44) | POLBGAASMN1; SMN2SSTR4KDM4E | |
| SCHEMBL24262284 | 0.85 | SSTR4 (0.38) | POLBGAASMN1; SMN2SSTR4KDM4E | |
| SCHEMBL7300865 | 0.84 | SSTR4 (0.42) | GAASMN1; SMN2SSTR4NOTUMTRPV1 | |
| SCHEMBL3930074 | 0.84 | POLB (0.46) | POLBGAASMN1; SMN2SSTR4 | |
| SCHEMBL3923944 | 0.84 | POLB (0.46) | POLBGAASMN1; SMN2SSTR4 | |
| SCHEMBL21798462 | 0.84 | SSTR4 (0.41) | GAASMN1; SMN2SSTR4KDM4ETRPV1 | |
| SCHEMBL27720908 | 0.81 | SSTR4 (0.40) | GAASMN1; SMN2SSTR4MAPK1 | |
| SCHEMBL28001849 | 0.81 | TRPV1 (0.40) | GAAKDM4ETRPV1 | |
| SCHEMBL29208044 | 0.80 | SSTR4 (0.46) | SSTR4KDM4ETRPV1MAPK1PKM | |
| SCHEMBL28788365 | 0.80 | KDM4C (0.43) | GAASMN1; SMN2KDM4ETRPV1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466934-B1 | SULFONAMIDE COMPOUNDS OR SALT THEREOF AS RIBONUCLEOTIDE REDUCTASE INHIBITORS FOR TREATING CANCER | TAIHO PHARMACEUTICAL CO LTD (JP) | 2024-03-27 | — | — | EP | disclosed |