⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644987 | 0.74 | — | — | |
| SCHEMBL16236607 | 0.74 | — | — | |
| SCHEMBL21644980 | 0.74 | — | — | |
| SCHEMBL8719833 | 0.72 | — | — | |
| SCHEMBL16236404 | 0.69 | — | — | |
| SCHEMBL7068052 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL17956602 | 0.69 | — | — | |
| SCHEMBL8574174 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL51026 | 0.67 | — | — | |
| SCHEMBL18824509 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4136096-A | REACTING A 3-CYANO-PENAM WITH AN AZIDE | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |