Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612065 | 0.87 | CNR1 (0.48) | CNR1CNR2NPC1RAB9ACFTR | |
| SCHEMBL1627157 | 0.85 | CNR1 (0.51) | CNR1CNR2SMN1; SMN2TSHRMCHR1 | |
| SCHEMBL730020 | 0.82 | CNR1 (0.52) | CNR1CNR2RAB9ACFTRALDH1A1 | |
| SCHEMBL15383148 | 0.81 | CNR2 (0.48) | CNR1CNR2RAB9AALDH1A1GAA | |
| SCHEMBL1626715 | 0.81 | CNR1 (0.48) | CNR1CNR2RAB9AGAASMN1; SMN2 | |
| SCHEMBL25171663 | 0.81 | CNR2 (0.48) | CNR1CNR2CFTRALDH1A1GAA | |
| SCHEMBL29990598 | 0.81 | CNR2 (0.48) | CNR1CNR2CFTRALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6978330 | 0.79 | ALDH1A1 (0.50) | CNR1CNR2NPC1RAB9ACFTR | |
| SCHEMBL31357589 | 0.79 | CNR2 (0.60) | CNR1CNR2RAB9ACFTRALDH1A1 | |
| SCHEMBL23582257 | 0.79 | CNR2 (0.60) | CNR1CNR2RAB9ACFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042870-A1 | DP ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-02-06 | — | — | US | disclosed |
| EP-3854781-B1 | DP ANTAGONISTS | ONO PHARMACEUTICAL CO (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-20220204468-A1 | DP ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-30 | — | — | US | disclosed |
| US-11319296-B2 | DP antagonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-05-03 | — | — | US | disclosed |
| US-20220033371-A1 | DP ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-02-03 | — | — | US | disclosed |
| EP-3854781-A1 | DP ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2021-07-28 | — | — | EP | disclosed |
| CN-112739680-A | DP antagonists | 小野药品工业株式会社 | 2021-04-30 | — | — | CN | disclosed |
| WO-2020059790-A1 | DP ANTAGONIST | 小野薬品工業株式会社 | 2020-03-26 | — | — | WO | disclosed |
| EP-1666473-B1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| CN-1882554-A | Carboxylic acid compounds and pharmaceutical compositions containing them as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2006-12-20 | — | — | CN | disclosed |
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033371-A1 | DP ANTAGONIST | OPRL1, CNR1, NPSR1 | CNR1 2/4885CNR2 4/4885NPC1 553/4885 |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | GPR17, CYSLTR1, KIT | CNR1 133/4885CNR2 157/4885NPC1 1788/4885 |
| US-20220204468-A1 | DP ANTAGONIST | OPRL1, CNR1, NPSR1 | CNR1 2/4885CNR2 4/4885NPC1 553/4885 |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | GPR17, CYSLTR1, KIT | CNR1 133/4885CNR2 157/4885NPC1 1788/4885 |
| US-11319296-B2 | DP antagonist | OPRL1, CNR1, NPSR1 | CNR1 2/4885CNR2 4/4885NPC1 553/4885 |
| US-20250042870-A1 | DP ANTAGONIST | OPRL1, CNR1, NPSR1 | CNR1 2/4885CNR2 4/4885NPC1 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.